Gamma | Comparison and Review of GB EF% on the Anterior

Comparison and Review of GB EF% on the Anterior and Right Lateral Images of Nuclear Hepatobiliary Scan

Eun-Byeol Lee, Jae-Il Kim, Yong-Ho Do, Jung-Jin Llm, Sung-Wook Cho, Gyeong-Woon Noh

Departmen Nuclear Medicine, Seoul National University Hospital, Seoul, Korea

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[Purpose] In case of nuclear medical hepatobiliary scan, To quantitatively evaluate contractility of a gallbladder, gallbladder ejection fraction (GBEF) is calculated from anterior images using fatty meal. However, when a gallbladder and other organs overlap on an anterior image , the gallbladder ejection fraction is not accurately evaluated. In order to reduce this error, the objective of our study was to figure out whether there is a significant difference in GB EF% calculated from the anterior and right lateral images.

[Materials and Method] After intravenous injection of 99mTc-Mebrofenin 400 ± 60 MBq to randomly 50 patients who visited our hospital, we started to examine nuclear hepatobiliary scan. Using skylight(Philips, United States), we acquired anterior and right lateral image at 10 minutes, 20 minutes, 30 minutes, 60 minutes, 90minutes after injection. Using images at 60 and 90 minutes, gallbladder ejection fraction (GBEF) was calculated from the anterior and right lateral images using JETstream workspace. For drawing more accurate ROI, CT images were referenced and 4 radiologists calculated the GBEF% in the same image and calculated the average value. We assessed whether there was a significant difference in GB EF% calculated from the anterior and right lateral images using SPSS program(Statistical Package for the Social Science, SPSS Ver.18 Inc. USA).

[Results] About randomly 50 patients, the average value of the GB EF% calculated from the anterior image was 63.212 and the average value of the GB EF% calculated from the right lateral image was 62.666. GB EF% decreased 0.433% on the right lateral image compared with anterior image. Result of paired sample t-test, p value is over 0.05. So, there was no significant difference in GB EF% calculated from the anterior and right lateral images.

[Conclusion] In the case that a gallbladder and other organs are not separated on an anteior image, Right lateral image would be better to acquire more accurate GB EF% than using anterior image.

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[Keywords] Hepatobiliary Scan, GB %EF, Anterior view image, Right lateral view image