Gamma | Radium-223 Dichloride의 외부 방사선량의 평가
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작성자 : 서울대 핵의학과 작성일2017-02-01 조회3,602회관련링크
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서울대학교병원 핵의학과
조성욱·윤석환·승종민·김태엽·임정진·김진의
The Evaluation of External Radiation Exposure dose rate for Radium-223 Dichloride
Seong Wook Cho, Seok Hwan Yoon, Jong Min Seung, Tae Yub Kim, Jeong Jin Im, Jin Eui Kim
Department of Nuclear Medicine, Seoul National University Hospital
Purpose :
223Ra-Dichloride is used for the medicine of castration-resistant prostate cancer (CRPC) and which
emits α-ray of 28 Mev that is used for therapy. However 223Ra-Dichloride emits β-ray of 3.6% and
γ-ray of 1.1%(80,156,270 keV) aside from α-ray in decay. Therefore we would like to evaluate
external radiation expose dose rate of γ-ray of 223Ra-Dichloride.
Materials and Methods :
We calculated external radiation expose dose rate using γ-constant of 223Ra-Dichloride, 99mTc based
on Health physics(2012). 223Ra-Dichloride of 3.5 M㏃ and 99mTc-MDP of 740 M㏃ were applied. external
radiation expose dose rate 15 times from 1m by survey meter.
Results :
γ-contant of 223Ra, 99mTc-MDP from 1m distance based on Health physics(2012) is 0.0469, 0.0215.
calculated value of external radiation expose dose rate was 16 μ㏜, 34 μ㏜ which activity is
223Ra-Dichloride of 3.5 MBq and 99mTc-MDP of 740 M㏃ from 1 m . and measured mean value of 1 m
was 0.7 μ㏜/h, 18 μ㏜/h.
Conclusion :
γ-constant of 223Ra is higher than 99mTc based on Health physics(2012). however calculated maximum
external radiation expose dose rate of 223Ra-Dichloride is lower than 99mTc due to actually used
quantity of activity of 223Ra-Dichloride is small. measured value of 223Ra-Dichloride is also lower
than 99mTc-MDP. Therefore external radiation expose dose rate of γ-ray of 223Ra-Dichloride is very
low.
Key Words : 223Ra-Dichloride, external radiation expose dose