PET | Evaluation of Database Comparison Methods for 18F-FDG Brain

PET/CT

Department  of  Nuclear  Medicine,  Seoul  National  University  Hospital,  Seoul,  Korea

Yong Ho Do  ． Hong  Jae Lee ． Jin Eui Kim

[Purpose]     Various    database    comparison   methods(DCM)   are     used    for     analyzing    functional neuro-imaging.  It is possible to statistically  evaluate decreased or  increased  metabolism of  abnormal patient's  brain   by  comparing with  normal  database  in  DCM.  And   results  of  DCM  are   additionally used  for   easily  explaining  defect  region.    The  aim   of   this  study  was  to  evaluate  usefulness  of Statistical Parametic Mapping(SPM) and  Scenium.

[Material  and  Method] Data of  15  patients(63.02±15.03 year)  underwent  18F-FDG  brain   PET/CT were collected  and   analyzed.  Biograph  TruePoint  40  with  TrueV,   (Siemens)  was  used  as  a   PET/CT scanner.  Scenium(version 4.0)  in  Syngo.via(version VA30A)   and   SPM99   were   applied   for  statistical evaluation. Preference test and  coherency between report from  image  reading and  result of DCM  were evaluated  by   5  nuclear  medicine physicians  through  a  questionnaire survey.  And   average  required time for  generating result of SPM99  and  Scenium was compared by  3 medical  technologists.

[Results]　Coherency  from  the result of  SPM99  and  Scenoum showed 84%  and  88%  compare to report of  image   reading. Scenoum acquired higher  score  than  SPM99   in  preference test.  Average required

time of  SPM99   and  Scenium took 282  seconds and  116  seconds to generate result. And  run-time  of

Scenium took 58.8% shorter than SPM99.

[Conclusion]  Results of  SPM99   and  Scenium showed  coherency compare to report  of  image   reading.. Various parameters  can  be  controled by  user when   using SPM.   However, normal database  needs to be  acquired.  And   it  takes  significant amount of  time  and  effort  for  the first  set  up.  On  the other hand,   Scenium provides normal  database  even   though  modifiable parameters  are   limited.  Therefore, more  informations could  be  provided for  brain   PET/CT if  properly understanding  and  selecting each DCM.

[Key  Words]  Brain  PET/CT,  Neuro-imaging,  SPM,  Scenium