Gamma | 99mTc-HMPAO를 이용한 Brain SPECT Study에서 Dynamic Brain SPECT
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작성자 : 서울대 핵의학과 작성일2017-02-01 조회3,744회관련링크
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서울대학교병원 핵의학과
조성욱. 문일상. 김진의. 조규진
Dynamic Brain SPECT in the Brain SPECT Study by using 99mTc-HMPAO
Seung Wook Cho, Il Sang Moon, Jin Eui Kim, Kyu Chin Cho
Department of Nuclear Medicine Seoul National University Hospital
=Abstract
Purpose:
Basal Brain SPECT study has been done by setting 20~30 sec/frame after injection of
99mTc-HMPAO. We want to discuss the availability of using Dynamic Brain SPECT in Brain SPECT
study by setting the ROI to brain blood flow region per time and making the quantitative analysis.
Methods:
1. Collect the Dynamic Brain SPECT image made by using Prism3000(3head camera) LHER-fan beam
collimator.(128×128 word mode, 1sec/3°/40frame, collection of total twenty five raw data)
2. After collection of Dynamic Brain SPECT image, you can obtain the raw data of Basal Brain
SPECT by setting 20-30sec/3°/frame and 128×128 word mode.
3. Get each coefficient variation by setting twenty five ROI upon the collected Dynamic Brain SPECT
data.
4. Analyse the change per time by each coefficient.
5. Get each coefficient variation by setting twenty five ROI upon the Basal Brain SPECT data.
6. Analyse the Dynamic Brain SPECT data by interval of 40sec, and simultaneously compare them
with Basal Brain SPECT data.
Results:
In Dynamic Brain SPECT, Whole Brain(40sec/interval) radioactivity coefficient variation
was 15~20count/pixel on average and it showed constant Plateau on the time-radioactivity curve.
In the quantitative analysis of Dynamic Brain SPECT and Basal Brain SPECT, Basal Right/Left mean
ratio was 0.7-1.47 as comparing twelve ROI, Dynamic Right/Left mean ratio 0.67-1.38, Basal
Right/Left max ratio 0.86-1.31, and Dynamic Right/Left max ratio 0.87-1.27 .
Conclusion:
When we get projection data from Dynamic Brain SPECT by 1sec/frame with injection, The
availability is First, basal brain flow image can be obtained by add file.
And another, brain blood SPECT study can be displayed by quantitative analysis of twenty five ROI
per time.
Key Word : Basal Brain SPECT, Dynamic Brain SPECT